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ROXICODONE (oxycodone hydrochloride) ® could cause spasm with the sphincter of Oddi and may be utilized with warning in patients with biliary tract disease, together with acute pancreatitis. Opioids like ROXICODONE (oxycodone hydrochloride) ® may perhaps lead to will increase from the serum amylase amount.ROXICODONE (oxycodone hydrochloride) ®,